COVISHIELD, the COVID Vaccine of India is being manufactured by _________. 

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Uttarakhand Police Constable Official Paper (Held On: 18 Dec 2022)
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  1. Bharat Biotech
  2. Panacea Biotech
  3. Serum Institute 
  4. Zydus Cadila

Answer (Detailed Solution Below)

Option 3 : Serum Institute 
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Detailed Solution

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The correct answer is Serum Institute.

Key Points

  • COVISHIELD is one of the primary COVID-19 vaccines used in India.
  • It is developed by AstraZeneca and the University of Oxford.
  • The vaccine is manufactured and distributed in India by the Serum Institute of India (SII), located in Pune.
  • The Serum Institute is the world's largest vaccine manufacturer by volume and has played a crucial role in supplying COVID-19 vaccines globally.
  • It uses a viral vector platform to stimulate an immune response against the SARS-CoV-2 virus.

Additional Information

  • Viral Vector Vaccines
    • These vaccines use a modified version of a different virus (the vector) to deliver genetic material from the virus that causes COVID-19.
    • Once inside our cells, this genetic material gives instructions to make a protein that is unique to the COVID-19 virus.
    • Our cells display the protein on their surface, which triggers an immune response.
  • Emergency Use Authorization (EUA)
    • It allows the use of unapproved medical products to diagnose, treat, or prevent serious or life-threatening diseases during an emergency.
    • Covishield received EUA in India in January 2021.
  • Cold Chain Requirements
    • Covishield needs to be stored at 2-8 degrees Celsius, which is within the normal refrigerator temperature range.
    • This storage requirement makes it easier to handle and distribute compared to vaccines needing ultra-cold storage.
  • Global Distribution
    • Serum Institute has supplied Covishield to several countries under the COVAX initiative, aimed at equitable access to COVID-19 vaccines.
    • India is one of the largest producers and exporters of vaccines globally.
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