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Option 2 : 19-5-2025 IMG-649 Ankit -21

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CONCEPT:

Formation of Grignard Reagent and Subsequent Cyclization

  • When an alkyl halide is treated with magnesium (Mg) in dry ether, a Grignard reagent (RMgBr) is formed.
  • The Grignard reagent is highly reactive and can undergo intramolecular reactions, especially when a halide group is present on the same molecule.
  • This can lead to the formation of cyclic structures if the conditions favor such an intramolecular attack.

EXPLANATION:

  • In this reaction, the presence of two bromine atoms in close proximity leads to the formation of two Grignard reagents.
  • One of the Grignard reagents can perform an intramolecular attack on the other carbon atom bearing the second bromine, leading to the elimination of MgBr2.
  • This intramolecular reaction results in the formation of a three-membered cyclopropane ring as the major product, as shown in option (2).

19-5-2025 IMG-649 Ankit -24

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