Which of the following organism produces statins?

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AIIMS BSc NURSING 2023 Memory-Based Paper
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  1. Monascus purpureus
  2. Trichoderma polysporum
  3. Aspergillus niger
  4. Clostridium butylicum

Answer (Detailed Solution Below)

Option 1 : Monascus purpureus
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AIIMS BSc NURSING 2024 Memory-Based Paper
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The correct answer is Monascus purpureus

Explanation:

  • Statins produced by the yeast Monascus purpureus have been commercialised as blood-cholesterol lowering agents. It acts by competitively inhibiting the enzyme responsible for synthesis of cholesterol. 
  • Cyclosporin A, that is used as an immunosuppressive agent in organ-transplant patients, is produced by the fungus Trichoderma polysporum.
  • Aspergillus niger is known for producing Citric acid.
  • Clostridium butylicum is known for producing Butyric acid.
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