Match List - I with List - II.

List - I		List - II
(A)	Streptokinase	(I)	Blood-Cholesterol lowering agents
(B)	Cyclosporin A	(II)	Clot Buster
(C)	Statins	(III)	Propionibacterium Sharmanii
(D)	Swiss Cheese	(IV)	Immuno suppressive agent

Choose the correct answer from the options given below:

Concept:

• Microbes play an important role for the production of industrial products.
• They are used for fermented beverages, antibiotics, bioactive molecules as well as food products like cheese.
• Microbes may include bacteria as well as fungi.

Important Points

• Streptokinase - 
  • Streptokinase is known as a 'clot buster'.
  • Streptococcus bacteria are used industrially to produce Streptokinase.
  • It is used to remove unwanted blood clots in the blood vessels.
  • It is particularly useful in patients who have undergone myocardial infarction leading to heart attack.
  • The bacteria Streptococcus may also be genetically modified to produce the desired bioactive molecule.
• Cyclosporin A - 
  • ​Cyclosporin A is produced from the fungus Trichoderma polysporum.
  • Cyclosporin A is used as an immunosuppressive agent in organ transplant patients.
• Statins - 
  • Statins are blood cholesterol-lowering agents.
  • It can induce competitive inhibition of the enzyme responsible for synthesis of cholesterol.
  • It can be industrially obtained from a type of yeast called Monascus purpureus.
• Swiss Cheese -
  • ​Swiss cheese are formed by the bacterium Propionibacterium shermanii.
  • The large holes seen in Swiss cheese are its characteristic feature.
  • They are formed due to CO₂ production by the bacterial respiration.

Corrected Table:

Hence, the correct answer is option 2.